Research Advisor, Computational Chemistry

About us:

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About our client:

Global healthcare leader headquartered in Indianapolis, Indiana. The Cardiometabolic Research (CMR) Therapeutic Area of our client, focuses on the discovery of biologic, small molecule and genetic therapeutics for the treatment of cardiometabolic diseases and associated complications. 

We are seeking a highly motivated computational chemist to join our team and apply physics‑based modeling and cheminformatics to the design of chemically modified oligonucleotide therapeutics.

Oligonucleotide therapeutics—including siRNAs, ASOs, and splice‑switching oligonucleotides—occupy a unique chemical space between small molecules and biologics. Each position in a therapeutic oligonucleotide can carry distinct sugar, backbone, and base modifications, creating a vast combinatori...