Senior Scientist,Advanced MIDD & Quantitative Systems Pharmacology

We are building comprehensive Model-Informed Drug Development (MIDD) capabilities in-house to create reusable platform models across our oncology portfolio. We seek a talented and motivated expert to develop advanced Quantitative Systems Pharmacology (QSP) models in oncology that enable Virtual Population simulations. You will act as a MIDD expert for oncology and integrate this knowledge into Clinical Pharmacology strategy for related development programs.

This means:

• Develop QSP platform models for multiple oncology mechanisms including:
  
  
  
  
  • Immune checkpoint inhibitors (IO/ICI) across colorectal, lung, and ovarian cancers
  
  
  • Antibody-drug conjugates across lung, ovarian, and colorectal cancers
  
  
  • T-cell engagers and bispecifics/trispecifics in multiple myeloma
  
  
  • CAR-T therapies in hematologic malignancies
  
  
  
  


• Create and optimize Virtual Population...