Sr. Upstream Processing Technician

Actalent • Saint Louis, MO, United States • Posted June 13, 2026

Location Saint Louis, MO
Job Type Full-time
Category other-general
Posted June 13, 2026
Job Title: Upstream Processing TechnicianJob Description
Join a dynamic team in the pharmaceutical industry, supporting the manufacture of commercial and clinical biologics. As an Upstream Processing Technician, you will follow Current Good Manufacturing Practices (cGMPs) to perform various functions related to upstream cell culture, including mammalian cell propagation, aseptic operations, and large-scale bioreactor production.
Responsibilities

+ Review all area documents.

+ Manage the WNS.

+ Assist in the manufacture of controls and calibrators, completing batch records in compliance with cGMPs.

+ Perform in-process assays using equipment such as spectrophotometers, pH meters, and clinical analyzers.

+ Weigh, transfer, and mix chemicals.

+ Conduct product filtrations.

+ Clean and steam steel tanks (CIP/SIP).

+ Prepare glassware and steel tanks for sterilization in an autoclave and operate the autoclave.
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