Sr. Upstream Processing Technician

Actalent • Saint Louis, MO, United States • Posted June 03, 2026

Location Saint Louis, MO
Job Type Full-time
Category other-general
Posted June 03, 2026
Job Title: Upstream Processing TechnicianJob Description
The Upstream Processing Technician supports the manufacture of commercial and clinical biologics by performing upstream (cell culture) operations in a regulated, cGMP environment. This role focuses on mammalian cell culture, operation of large-scale bioreactors, and associated filtration or centrifugation activities while maintaining strict aseptic technique and accurate documentation. The position offers an excellent opportunity to gain hands-on experience with large-scale biological and pharmaceutical manufacturing processes that contribute to the production of biologic therapies.
Responsibilities

+ Execute manufacturing batch records, work instructions, and standard operating procedures (SOPs) with a proactive focus on accurate, ‘right the first time’ completion.

+ Assist with batch record reconciliation and ensure all required documentation is complete, accurate, and compliant with cGMP standards.
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